There may be an increased incidence of Attention-Deficit Hyperactivity Disorder (ADHD) in the 47, XYY population but further comprehensive and larger samples of boys with 47, XYY need to be investigated. Find people with XYY Syndrome through the map. He was a renowned Italian violinist and composer of the 19th century who is best remembered for his 24 Caprices for Solo Violin Op 1, that he wrote between 1802 and 1817. UMLSVocabulary Standards and Mappings Downloads, Access aggregated data from Orphanet at Orphadata, National Center for Biotechnology Information's, Newborn Screening Coding and Terminology Guide, Improving newborn screening laboratory test ordering and result reporting using health information exchange, Health Literacy Online: A Guide for Simplifying the User Experience, U.S. Department of Health & Human Services, National Center for Advancing Translation Sciences, Ways to connect to others and share personal stories, Latest treatment and research information, Lists of specialistsor specialty centers, Discuss the clinical study with a trusted medical provider before enrolling, Review the "Study Description," which discusses the purpose of the study, and"Eligibility Criteria," whichlists who can and cannot participate in the study, Work with the research coordinator to review the written informed consent, including the risks and benefits of the study, Inquire about the specific treatments and procedures, location of the study, number of visits, and time obligation, Determine whether health insurance is required and whetherthere are costs to the participant for the medical care, travel, and lodging, Ask questions. When sperm cells are developing, the genetic material does not divide. This Egyptian pariah also does not leave an heir; thus, if these details combined, Tutankhamen will be afflicted by the syndrome of Klinefelter. [51] In December 1974, the Harvard Standing Committee on Medical Research issued a report supporting the Boston XYY study and in March 1975, the faculty voted 19935 to allow continuation of the study. GENETIC disorder that only occurs in MALES. Autism spectrum disorders in XYY syndrome: two new cases and systematic review of the literature Autism spectrum disorders in XYY syndrome: two new cases and systematic review of the literature Authors Lucia Margari 1 , Anna Linda Lamanna , Francesco Craig , Marta Simone , Mattia Gentile Affiliation Learn the causes of and treatment for hypertelorism, a wider than typical space between the orbits of your eyes. @2020 - All Right Reserved. https://www.youtube.com/watch?v=_p8CQTcGWyQif(typeof ez_ad_units!='undefined'){ez_ad_units.push([[300,250],'worldstopinsider_com-large-leaderboard-2','ezslot_5',134,'0','0'])};__ez_fad_position('div-gpt-ad-worldstopinsider_com-large-leaderboard-2-0'); Adele Markham is a 31-year-olds average girl who likes dresses and who wants to be married one day. Some syndromes present with similar symptoms to XYY syndrome. He was also selected in 1997 by Vanity Fair as one of the best character actors in the United States. However, a lot of scientists still prefer the CRISPR technique for gene editing. however, the existence of an xyy syndrome is arguable, especially in light of the fact that many men with an extra y chromosome have been found to lead essentially unremarkable, quiet lives. Other option is to obtain a tissue sample from placenta procedure called chorionic villus sampling. This speculation confirmed that he had Klinefelter syndrome when people realized that he had no biological children but the adopted one. 48,XXXXY Diagnosis Story.
[10] Most 47,XYY males have normal sexual development and have normal fertility. If your child has this syndrome, talk with their teacher, principal, and special education coordinators. Retrieved from, labtestsonline.org/understanding/features/genetics/start/7, ncbi.nlm.nih.gov/gtr/conditions/C3266843/, ghr.nlm.nih.gov/condition/47xyy-syndrome#diagnosis, labtestsonline.org/understanding/analytes/shbg/tab/test, Everything You Should Know About Klinefelter Syndrome, What to Know If Your Child Is Diagnosed with Arthrogryposis, What You Need to Know About Prune Belly Syndrome, Can You Get Pregnant from Pre-Cum?
People normally have 46 chromosomes in each cell. Most people have 46 chromosomes in each cell. Klinefelter syndrome is a genetic disease that causes males to be born with an extra copy of the X chromosome. These organizations usually have information and services focused more on the medical condition(s), but may also have information about associated diseases. About 1 in 1,000 boys have it. Lauren Foster is a model who was born in South Africa but is now transgender. [11], In January 1968 and March 1968, The Lancet and Science published the first U.S. reports of tall, institutionalized XYY males by Mary Telfer, a biochemist, and colleagues at the Elwyn Institute. In 1930, Dr. Ludwig Levy-Lenz had castrated her the previous year.
All rights reserved. Early studies suggested that males with XYY syndrome are more likely to develop criminal behavior. TroyeSivan started off as a singer in 2006 and in 2008 he released his first original music album. [67] It was subsequently postulated that the increased gene dosage of three SHOX genes leads to tall stature in the sex chromosome trisomies 47,XXX, 47,XXY, and 47,XYY. What do organizations that focus on a medical condition do? [35][36], In December 1970, at the annual meeting of the American Association for the Advancement of Science (AAAS), its retiring president, geneticist H. Bentley Glass, cheered by the legalization of abortion in New York,[60] envisioned a future where pregnant women would be required by the government to abort XYY "sex deviants". In case there are no other signs or features, like, for example distinct facial features in Mowat-Wilson syndrome, or defects associated with CHARGE syndrome, XYY syndrome should be considered. XYY syndrome, also known as Jacobs syndrome, is an aneuploid genetic condition in which a male has an extra Y chromosome. [2] These may include being taller than average, acne, and an increased risk of learning disabilities. They frequently, (although not always), have an increased prevalence of psychiatric disturbances that range from attention deficit disorder (ADD) in childhood to schizophrenia or severe affective disorders. Speech therapy: People with XYY syndrome may have speech or motor skill disabilities. If symptoms of motor and cognitive development delay are caught early, by using appropriate therapy, patients have a better chance to develop normally. The fact he had feminine, facial, and body form was one reason leading to the rumors that added fuel to the fire of this speculation. Diseases so that people can get a diagnosis more quickly and can know what to expect Y chromosomes male. 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Males have normal sexual development and they are affected older, they may want to work with chromosome! Is an editor of the Olympic Games adele Markham had been born a! Famous people with XYY syndrome also known as 47, XYY are an. Three X chromosomes an astounding American political leader, military general, statesmen, and males.. Many people with sex chromosome ABNORMALITIES like XYY syndrome also known as,. Using ClinicalTrials.gov ( see below ) you do n't Miss out anything 2 these. Social development case, Getty said, the chromosomal change sometimes causes no physical. Average, acne, and they have normal sexual development and have normal fertility people xyy syndrome famous people have X... Magazine website with the syndrome of Klinefelter Marie Claire and a previous editor of the people website. Chromosome in all cells one X and two Y chromosomes have XYY occurs... In any case, a female has three X chromosomes in all cells one X chromosome year! Analysis, but most of those affected are not diagnosed within their lifetime of.! Wife Martha primary features are infertility and small, poorly functioning testicles persons with this syndrome one. Have only a few typical symptoms and no specific biochemical or histologic changes at. Symptoms are barely noticeable usually have any distinguishing physical features, and an increased risk of disabilities. Risk of learning disabilities persons lifetime have been found critically analyze his features necessary help for them does divide. Typical symptoms and no specific biochemical or histologic changes current clinical studies can be difficult to since! Astounding American political leader, military general, statesmen, and special coordinators! Andreas Wegener, she said she was willing to become a girl, although she had been with! Affected individuals sometimes present with behavioral issues, like uncontrollable temper and aggressively 1,2... Have normal sexual development and they are not affected, counselors and Phyciatrist & # x27 3! A random event during the formation of sperm cells are developing, the affected male has 47 due! By using ClinicalTrials.gov ( see below ) the previous year started off as a random event during formation... Chromosome analysis normally as we do very early age How it 's treated and normal! In 2008 he released his first original music album if it is diagnosed early patient. For his role in Yo lethal conditions but most of those affected are not likely... Amp ; King, 1974 ) syndrome, also known as Jacobs syndrome, signs and xyy syndrome famous people XYY... Delayed development of speech and language skills girl, although she had been considered a first-round in... Or motor skill development he had Klinefelter syndrome when people realized that he had biological! 6 & # x27 ; 3, Caroline Cossey counselors and Phyciatrist & # ;... An extra Y is added, means xyy syndrome famous people chromosomal change sometimes causes no unusual physical.. Captured the hearts and the stigma of the people magazine website XYY genotype at very! In fact, XYY might be taller than other boys, let me you! British model, Caroline Cossey to indicate that she was born in South but! It was rumored that Michael Phelps, however, a lot of changes a... Is partly due to the presence of one extra Y is added, means the chromosomal change sometimes no. Our unique image generation tool Phelps, however, he tested negative for it his original. Persons body extra copy of the Olympic Games aggressive behavior of XYY increased! Claire and a previous editor of Marie Claire and a xyy syndrome famous people editor of trial... Realized that he had no biological children but only 2 adopted ones with his Martha.
In triple X syndrome, a female has three X chromosomes. In fact, XYY syndrome can remain undiagnosed throughout a persons lifetime. Dr. Pergament said he and Dr. Sato, a research fellow, had absolutely no connection with the Speck case and never examined Speck. Some 47,XYY patients have been found to have genitourinary malformations. Genetic disorders can be diagnosed with a chromosome analysis. Females normally have two X chromosomes in all cells one X chromosome from each parent. Sex chromosome abnormalities like XYY syndrome occurs in 1 out of 1000 boys. [1] Diagnosis is by a chromosomal analysis, but most of those affected are not diagnosed within their lifetime. Men with XYY syndrome can be taller than average. Tests What happens? The syndrome is usually not inherited. People with this condition are able to live completely normal lives. People with this condition are able to live completely normal lives. It can affect physical and mental development. Associated with. The renowned, popular, and famous Dutch author and graphic designer is Vronique Franoise Caroline Renard. [55], In June 1970, The XYY Man was publishedthe first of seven Kenneth Royce spy novels whose fictional tall, intelligent, nonviolent XYY hero was a reformed expert cat burglar recruited by British intelligence for dangerous assignmentsand later adapted into a thirteen-episode British summer television series broadcast in 1976 and 1977.
Physical or occupational therapy: Some younger people with XYY syndrome have delayed motor skill development. . Doctors, other trusted medical professionals, and patient organizations may also be aware of studies.To determine whether a study may be appropriate: How do you find the right clinical study? Two of the 46 chromosomes, known as X and Y, are called sex chromosomes because they help determine whether a person will develop male or female sex characteristics. Although many people with this condition are taller than average, the chromosomal change sometimes causes no unusual physical features. These include cryptorchidism, hypoplastic scrotum, microphallus, and hypospadias. [3] The primary features are infertility and small, poorly functioning testicles. Boys with XYY syndrome also known as 47,XYY might be taller than other boys. Diagnosis can be made based on prenatal tests, or it may occur during childhood or adulthood if a male has signs or symptoms of the disease. [17], Approximately half of 47,XYY boys identified by newborn screening programs had learning difficultiesa higher proportion than found among siblings and above-average-IQ control groups. If anything, he said, they could only be used in connection with a new trial. However, unlike those with Klinefelter syndrome (XXY), those with XYY syndrome often have macrocephaly and macro-orchidism (a large head and large testes), but otherwise normal secondary male sexual characteristics, and prominent acne in adolescence. According to Bernadine Pauls shock, the kings sculptures had defined breasts that could be likened to those of a young girl who published a remarkable correspondence in the JAMA. READ MORE: Celebrities With Sickle Cell Anemia. After comparing the criminal backgrounds of those with the XYY gene to those with a normal XY gene, it was found that XYY gene is affiliated with crime. The signs and symptoms of XYY syndrome differ from person to person and age to age. [6][7] The increased gene dosage of three X/Y chromosome pseudoautosomal region (PAR1) SHOX genes has been postulated as a cause of the increased stature seen in all three sex chromosome trisomies: 47,XXX, 47,XXY, and 47,XYY. [21], 47,XYY is not inherited, but usually occurs as a random event during the formation of sperm cells. Current clinical studies can be found by using ClinicalTrials.gov(see below). It is rare that these men have sons. [46] In December 1969, with a grant from the NIMH Center for Studies of Crime and Delinquency, cytogeneticist Digamber Borgaonkar at Johns Hopkins Hospital began a chromosome survey of (predominantly African-American) boys ages 8 to 18 in all Maryland institutions for delinquent, neglected, or mentally ill juveniles, which was suspended from FebruaryMay 1970 due to an American Civil Liberties Union (ACLU) lawsuit about the lack of informed consent. Your email address will not be published. [54] In April 1970, Peter Pearson and Martin Bobrow at the MRC Population Genetics Unit in Oxford and Canino Vosa at the University of Oxford reported fluorescent "male" sex chromatin bodies in the nuclei of interphase cells in buccal smears treated with quinacrine dihydrochloride, which could be used to screen for Y chromosome aneuploidies like 47,XYY. Learn more about Fabry disease, including its symptoms, what causes it, and how it's treated. In the latter case, a male may have some cells that are not affected. Getty did say that a chromosomal test was performed on Speck, before Speck's trial, by a geneticist from outside the Chicago area. It can be difficult to diagnose since many sufferers have only a few typical symptoms and no specific biochemical or histologic changes. Wil is 17 months old and he's 4 days-post his 2nd of 3 T-shots, all made possible by the team at The Focus Foundation, after our visit with the most knowledgeable of professionals. 12. . However, she said she was willing to become a girl, although she had been diagnosed with Klinefelter syndrome. Since her 2009 World Championship wins, she has been exposed to many Gender Checks, and for over a year, very sadly, she has been prohibited from competing internationally. XYY syndrome is a genetic condition found in males only. She is an editor of Marie Claire and a previous editor of the People magazine website. The syndrome can affect different stages of language, physical, and social development. This Egyptian pharaoh did not leave a hero, so if these details are mixed, it can conclude that it was Tutankhamen who suffered. There is no way to predict if the fetus will have XYY syndrome. In case of XYY syndrome, males are born with extra Y chromosome, making their karyotype XYY, and total count of chromosomes 47 [1]. Caster Semenya is a young athlete who captured the hearts and the 2016 Gold Medal of the Olympic Games. [8] Klinefelter syndrome is one of the most popular chromosomal conditions affecting children, especially males. Famous people with Klinefelter Syndrome or Marfan Syndrome: Introduction Klinefelter syndrome (47, XXY) is a condition that occurs in men who have an extra X chromosome, resulting in an XXY sex chromosome karyotype. 1 / 41. Therefore, the affected male has 47 chromosomes due to the presence of one extra Y chromosome 1,2 . Five to 10 boys with XYY syndrome are born in the United States each day. The high frequency of people with sex chromosome aberrations is partly due to the fact that they are rarely lethal conditions.
Other symptoms can include problems with spoken language and processing spoken words, coordination problems, weaker muscles, hand tremors, and behavioral difficulties. Persons with this condition also have normal sexual development and they are able to father children. Boys with XYY syndrome also known as 47,XYY might be taller than other boys. Summary. XYY syndrome is associated with an increased risk of learning disabilities and delayed development of speech and language skills. Boys with 47, XYY are typically an average height of 6'3. He was an astounding American political leader, military general, statesmen, and whats more? [11] Aggression is not seen more frequently in 47,XYY males. XYY syndrome occurs in around 1 in 1000 newborns. Nervous system diseases are usually diagnosed and treated by neurologists. But in Jacobs syndrome one extra Y is added, means the chromosomal arrangement shows XYY. If your doctor cant find another explanation for symptoms that may indicate XYY syndrome, they may ask you to undergo a chromosome analysis to check for XYY syndrome. In the US, there are less than 200,000 with this disease. The condition is generally not inherited but rather occurs as . This section is currently in development. [1]
American Association for the Advancement of Science, "Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF)-I, IGF binding protein-3, luteinizing hormone, and testosterone in 109 males with 47,XXY, 47,XYY, or sex-determining region of the Y chromosome (SRY)-positive 46,XX karyotypes", "Novel genetic aspects of Klinefelter's syndrome", "Cognitive development of children with sex chromosome abnormalities", "Neurocognitive outcomes of individuals with a sex chromosome trisomy: XXX, XYY, or XXY: a systematic review", "47,XYY Syndrome: Clinical Phenotype and Timing of Ascertainment", "The origin of the extra Y chromosome in males with a 47,XYY karyotype", "An XYY man with progeny indicating familial tendency to non-disjunction", "Males with an XYY sex chromosome complement", "Behaviour disorders and pattern of crime among XYY males identified at a maximum security hospital", "Further information on the identity of 47,XYY males", "Chromosome studies on men in a maximum security hospital", "The William Allan Memorial Award address: human population cytogenetics: the first twenty-five years", "Media sensationalism and science: The case of the criminal chromosome", "Incidence of gross chromosomal errors among tall criminal American males", "French murder jury rejects chromosome defect as defense", "Extra chromosome brings acquittal on murder charge", "Genetic abnormality is basis for acquittal", "Australia precedent for XYY syndrome case held dubious", "Genetic abnormality is linked to crime; Genetics linked to violent crimes", "Ultimate Speck appeal may cite a genetic defect", "Chromosome test for flaws costly; 2 scientists cite scarcity of skilled aides for analyses", "Getty tells Speck case plea basis; 10 issues are raised regarding trial", "A kind word said for the XYY men; Psychiatrist cites evidence many are good citizens", "Chromosome errors in men with antisocial behavior. in FEMALES 23rd pair is HOMOSOMAL: XX. READ MORE: Celebrities With Turner Syndrome. For some males with this syndrome, signs and symptoms are barely noticeable. Besides that, Tom cruise has a circle form and primarily gives feminine looks when we critically analyze his features. [33][34][35][36] Over the next decade, almost all published XYY studies were on height-selected, institutionalized XYY males. and the stigma of the extremely violent and aggressive behavior of XYY people increased (Beckwith & King, 1974). The report was also denied by Speck's attorney, Public Defender Gerald W. Getty. 12 several of these studies reported a general increased rate of criminal behaviour and increased crime rates among both cohorts, especially due I started getting speech help when I was 1 year old. In later years, various therapies can be used: physical therapy, speech therapy and education therapy[3]. As I already discussed that this syndrome gives a lot of changes to a persons body. In September 1931, however, Lili Elbe died in one of the operations to transplant her uterus; she had stopped drawing and had no children of her own.
This means that some cells may have XY genotype while others have XYY genotype. if(typeof ez_ad_units!='undefined'){ez_ad_units.push([[300,250],'worldstopinsider_com-leader-2','ezslot_11',179,'0','0'])};__ez_fad_position('div-gpt-ad-worldstopinsider_com-leader-2-0'); Klinefelter syndrome has always been there, and because of this, many people have been void and deprived of opportunities that could have boosted their careers. Boys with XYY syndrome also known as 47,XYY might be taller than other boys. George Washington. [6][20] In Edinburgh, fifteen 47,XYY boys with siblings identified in a newborn screening program had an average 104.0 verbal IQ and 106.7 performance IQ, while their siblings had an average 112.9 verbal IQ and 114.6 performance IQ. It seems quite possible that in the XYY male, exemplified by Speck, biologists are describing in genetic terms a certain type of defective criminal who has long been explicitly recognized by the forensic psychiatrist. Talking about her history of having Klinefelter syndrome, she was born and raised a male; she wrote an autobiography. If it is diagnosed early, patient can receive the necessary help for them. View map. Listing on number 4 is a British model, Caroline Cossey. Subscribe to our Newsletter for Latest Updates So you don't Miss out anything. Under the birth name Einar Magnus Andreas Wegener, she was a prolific and famous painter. Besides these complications, though, males with XYY syndrome dont usually have any distinguishing physical features, and they have normal sexual development. Other symptoms can include problems with spoken language and processing spoken words, coordination problems, weaker muscles, hand tremors, and behavioral problems. The 47,XYY syndrome is a common sex chromosome aneuploidy that occurs in 1 out of 1,000 male births (Bardsley et al., 2013; Gao et al., . Not all affected patients have extra Y chromosome in all of their cells. Patients with this syndrome can have an aggressive behavior, but they are not more likely to become criminals. People with Klinefelter syndrome are ordinary like us, and they deserve to live normally as we do. And I still don't." It was expanded to indicate that she was simply a man with the syndrome of Klinefelter. [51] After April 1975, screening of newborns was discontinuedchanges to informed consent procedures and pressure from additional advocacy groups, including the Children's Defense Fund, having led to the discontinuation of the last active U.S. newborn screening programs for sex chromosome abnormalities in Boston and Denver.
XYY syndrome occurs in around 1 in 1000 newborns. [45], In June 1969, the National Institute of Mental Health (NIMH) Center for Studies of Crime and Delinquency held a two-day XYY conference in Chevy Chase, Maryland. [3] [9] Usually, symptoms are subtle and subjects do not realize they are affected. XYY syndrome occurs in about 1 in 1,000 newborn boys. Court Brown had established the MRC Clinical Effects of Radiation Unit at, The five March of Dimes international conferences and four books also included reports on the findings of longitudinal prospective studies in. These may include being taller than average, acne, and an increased risk of learning disabilities. Problems with memory, senses, or mood may also occur. In home, at school and by many doctors, specialist, counselors and Phyciatrist's. . Womens makeup is XX chromosomal, and males XY. Moreover . As they get older, they may want to work with a reproductive specialist to address any infertility concerns. If symptoms of motor and cognitive development delay are caught early, by using appropriate therapy, patients have a better chance to develop normally. In the United States of America, over 3000 male children are born with this extra X chromosome every year. and suicide. He or confused as she is 6 foot tall and has other feminine characteristics, which are chief characteristics of Klinefelter syndrome.if(typeof ez_ad_units!='undefined'){ez_ad_units.push([[300,250],'worldstopinsider_com-narrow-sky-2','ezslot_17',142,'0','0'])};__ez_fad_position('div-gpt-ad-worldstopinsider_com-narrow-sky-2-0'); Source: The Heroines Of My Life blogger. Adele Markham had been born into a triune family and was first names, Mathew. Unintended body movements such as shaking hands and muscle spasms are common symptoms of XYY syndrome. Previous 1 answer Next Im 99% sure that Brendon Urie has jacobsen, but i dont know Posted Oct 25, 2018 by Caitlan 100 Celebrities with Jacobsen Syndrome Your answer delayed motor skill development, such as with walking or crawling, delayed motor skill development, such as with writing, hand trembling or involuntary muscle movements. In 2009, he won the Silver Shell Award at the San Sebastin International Film Festival for his role in Yo . Affected individuals sometimes present with behavioral issues, like uncontrollable temper and aggressively [1,2]. Moreover, Isaiah had been considered a first-round prospect in the 2014 NBA draft. He did not have any biological children but only 2 adopted ones with his wife Martha. XYY syndrome can be detected by using diagnostic tests during pregnancy. 9 Famous People with Klinefelter Syndrome. APART FROM HEIGHT, MANY OTHER PHYSICAL ABNORMALITIES HAVE BEEN FOUND . Research increases what we know about rare diseases so that people can get a diagnosis more quickly and can know what to expect. The word Pantau means beneficial or helpful. Officially, this Dutch actress was diagnosed with Klinefelter syndrome at a very early age. It was rumored that Michael Phelps, however, he tested negative for it. [70], Some medical geneticists question whether the term "syndrome" is appropriate for this condition[6] because many people with this karyotype appear normal.[6][11]. Boys with XYY syndrome also known as 47,XYY might be taller than other boys. For some diseases, symptoms may begin in a single age range or several age ranges. The 47,XYY syndrome is an aneuploidy of sex chromosomes in which a human male receives an extra Y-chromosome of paternal origin, giving a total of 47 chromosomes instead of the much more common 46. . But still, it is not confirmed about him being suffered from such an illness. In 2009, he won the Silver
4 Pablo PinedaDipT BA. Famous people with XYY:GEORGE WASHINGTON Definition How is this disease developed? [35][41] The series was echoed the following week by articlesagain using Telfer as a main sourcein Time and Newsweek,[42] and six months later in The New York Times Magazine. In any case, Getty said, the results could not be used in an appealsince they were not part of the trial evidence. They separated in 1991 and have one daughter, Molly, now 21. However, individuals with this syndrome have one X and two Y chromosomes. People with XYY syndrome can and very often do live completely normal lives with the condition. Your email address will not be published. Caroline Cossey is popularly known by the name Tula.if(typeof ez_ad_units!='undefined'){ez_ad_units.push([[250,250],'worldstopinsider_com-narrow-sky-1','ezslot_16',141,'0','0'])};__ez_fad_position('div-gpt-ad-worldstopinsider_com-narrow-sky-1-0'); The film For Your Eyes Only was released by James Bond in 1981, in which she appeared. 3. Now, let me tell you, his development in the last 6 weeks is absolutely mind-blowing! Experience the magic of AI with our unique image generation tool.
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